Minocycline-induced chronic interstitial nephritis?

Minocycline-induced chronic interstitial nephritis?

Acute interstitial nephritis is a rare complication of tetracycline therapy and there have been two case reports associated with minocycline [1,2]. In both cases the patients presented within 2 weeks of commencing the antibiotic with an acute febrile illness and loin pain, and an acute interstitial nephritis was confirmed on renal biopsy. We report a case of chronic interstitial nephritis in a ...

Reversible Fluindione-Induced Chronic Interstitial Nephritis

Fluindione is well known to induce acute drug-induced interstitial nephritis (IN). Most cases occurred soon after the onset of treatment. We report a unique case of severe subacute fluindione-induced IN diagnosed 2 years after the treatment was begun. Renal function dramatically improved after fluindione withdrawal and steroid therapy.

Protracted systemic illness and interstitial nephritis due to minocycline.

A severe hypersensitivity-like illness with acute renal failure, lymphadenopathy and skin rash is reported following minocycline treatment in a 16 year old male. Following haemodialysis and steroid therapy his illness remitted, only to recur on withdrawal of the steroids. With further steroid treatment he recovered completely. Lymphocyte function tests, performed in an attempt to positively inc...

Mesalazine induced interstitial nephritis.

5-Aminosalicylic acid (5-ASA) has structural similarities to both phenacetin and aspirin, which are known to cause 'analgesic nephropathy'. Because of the increasing use of 5-ASA, this paper draws attention to two cases of severe interstitial nephritis resulting from 5-ASA and emphasises the importance of monitoring renal functions of patients with inflammatory bowel diseases who are receiving ...

Ciprofloxacin-induced allergic interstitial nephritis.